HSD17B4 抗體，HSD17B4 抗體很好說明書現(xiàn)貨
Cat. Number: RS-11296R
Quantity size: 0.1ml （dilute with pH 7.4 0.01 M PBS or diluent of antibody）
Background: 17Beta-HSD4 （17Beta-hydroxysteroid dehydrogenase type 4） is also known as peroxisomal multifunctional enzyme/protein 2 （MFE-2/MFP-2）, D-bifunctional enzyme or 17-Beta Estradiol dehydrogenase type IV. It belongs to the 17Beta-HSD family of proteins that regulate the availability of steroids within various tissues throughout the body. 17Beta-HSD4 inactivates Estradiol through its oxidative activity but it is primarily involved in peroxisomal fatty acid and cholesterol Beta-oxidation. It has a multi-domain structure: the dehydrogenase domain is fused to a hydratase and a lipid transfer domain. 17Beta-HSD4 is a target protein of chromeceptin and it is essential for the downstream activation of Stat6. 17Beta-HSD4-deficient patients exhibit Zellweger-like syndrome and die within the first year of life. They display neuronal migration defects, facial dysmorphisms, severe hypotonia and convulsions in the neonatal period.
Specificity: ·anti- HSD17B4 is a rabbit monoclonal antibody unconjugated
·specific for HSD17B4 of rat and mo
·epitope mapping near the amino terminus of HSD17B4 of
hu, rat and mo origin
· use for western blotting, elisa, immunoprecipitation
and immunohistochemistry
· Protein A affinity chromatography purification, purity :>95%
· Isotype: IgG
· mol wt: 47kDa
HSD17B4 抗體，HSD17B4 抗體說明書Application: · Western blotting: 1:100-500
· Immunohistochemistry: 1:100-500
· ELISA: 1:500-1000
· Optimal working dilutions must be determined by the end user.
Storage: Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ºC.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
HSD17B4 抗體，HSD17B4 抗體說明書
