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閱讀：485發布時間：2013-10-15
Rabbit Anti-PDGF-α抗體現貨
Catalog Number :Rs-0196R
Quantity size : 0.1ml （dilute with pH 7.4 0.01 M PBS or antibody diluent ） Background:
Plaet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by plaets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heal the wound. Antiparallel disulfide-linked dimer of nonidentical （A and B） chains. Homodimers of A and B chains are implicated in transformation processes. The long form contains a basic insert which acts as a cell retention signal. A-A and B-B, as well as A-B, dimers can bind to the PDGF receptor. It belongs to the PDGF/VEGF growth factor family.Function : Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septumformation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB.Subunit : Homodimer; antiparallel disulfide-linked dimer. Heterodimer with PDGFB; antiparallel disulfide-linked dimer. The PDGFA homodimer interacts with PDGFRA homodimers, and with heterodimers formed by PDGFRA and PDGFRB. The heterodimer composed of PDGFA and PDGFB interacts with PDGFRA homodimers, and with heterodimers formed by PDGFRA and PDGFRB. Interacts with CSPG4.
Specificity : Anti-PDGF-α is Rabbit polyclonal antibody
specific for PDGF-αof Human, Mouse, Rat，Wheat
Application :
Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
商鋪：http://www.ly-nte.com/st132832/
主營產品：流式標記抗體，FITC,PE,CY3,5,7標記ELISA試劑盒、生化檢測試劑盒、金標檢測試劑盒、分子生物學試劑盒、進口國產胎牛血清、生物抗體、細胞，試劑耗材
智慧城市網 設計制作，未經允許翻錄必究 .? ? ?
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